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KILLER CELLS, LYMPHOKINE-ACTIVATED
Descriptors Found:
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DeCS
Descriptor
English
:
Killer Cells, Lymphokine-Activated
Descriptor
Spanish
:
Células Asesinas Activadas por Linfocinas
Descriptor
Portuguese
:
Células Matadoras Ativadas por Linfocina
Synonyms
English
:
LAK Cells
Lymphokine-Activated Killer Cells
Tree Number:
A11.118.637.555.567.537.500
A15.145.229.637.555.567.537.500
A15.382.490.555.567.537.500
Definition
English
:
Cytolytic
lymphocytes
with the unique capacity of killing natural killer (NK)-resistant fresh tumor
cells
. They are interleukin-2-activated NK
cells
that have no MHC (major
histocompatibility
complex) restriction or need for antigen stimulation. LAK
cells
are used for adoptive
immunotherapy
in cancer
patients.
Indexing Annotation
English
:
A 11 qualif; subpopulations: coord IM with
LYMPHOCYTE SUBSETS
(IM); DF: note short X ref
See Related
English
:
Immunotherapy, Adoptive
Interleukin-2
History Note
English
:
90
Allowable Qualifiers
English
:
chemistry
classification
cytology
drug effects
enzymology
immunology
metabolism
microbiology
pathology
physiology
parasitology
radiography
radiation effects
radionuclide imaging
secretion
transplantation
ultrastructure
ultrasonography
virology
Record Number:
24762
Unique Identifier:
D015979
Occurrence in VHL
:
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